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Predicting individual differences in task fMRI

Speaker: Assoc Prof Saad Jbabdi, FMRIB, John Radcliffe Hospital, Oxford, UK

Different individuals can exhibit markedly different patterns of brain activity even when asked to perform the same task. This variability is often attributed to task strategy or compliance. I will show that individual differences in brain responses are, to a large degree, inherent to the brain, and can be predicted from task-independent measurements collected at rest. Using the HCP database, I will show that a simple model that trained to relate task-independent measurements to task activity can predict task activation maps for unseen subjects in several behavioural domains. I will also show an application to pre-surgical planning in patients.

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